ABOUT HYPERTENSION

Hypertension matters.

Hyper-
tension
matters.

Hypertension is prevalent worldwide. Despite continual efforts to improve its management, blood pressure control rates have declined substantially over the past two decades. Untreated, hypertension can lead to many significant health problems — and many people don’t even realize they have it.

1.28 billion adults worldwide have hypertension.*

*World Health Organization; https://www.who.int/news-room/fact-sheets/detail/hypertension; accessed on 7/09/2023

~54M ~5M ~15M Patients treated for hypertension¹ Uncontrolled hypertension
(BP>140/90)¹ Resistant hypertension ¹ ²
(BP>140/90 and on 3+ medicines) • Ischemic heart disease, including myocardial infarction • Stroke • Heart failure • Chronic renal failure • Cognitive decline Left undetected or untreated over time, hypertension can lead to: A significant number of treated hypertension patients have resistant and/or uncontrolled hypertension¹
 1. Zhang et al. Hypertension. 2017 Oct;70(4):736-742. Online Supplement – 2013-14 Data.
2. Carey et al. Hypertension. 2019 Feb;73(2):424-431.

5

years

5
years

Hypertension is associated with five years reduced life expectancy.¹

1. Stroke and High Blood pressure correlation – AHA – High Blood Pressure and Stroke Infographic | American Stroke Association

Patients with resistant hypertension are at risk of heart disease and stroke — two of the leading causes of death worldwide.

~50%

of heart attacks and strokes are associated with high blood pressure¹

1. Lawes et al. Lancet. 2008 May 3;371(9623):1513-8

A 10 mmHg drop in office systolic blood pressure reduces risk by:¹

Meta-analysis of 613,815 patients from 123 studies.

A 10 mmHg drop in office systolic blood pressure reduces risk by:¹

Meta-analysis of 613,815 patients from 123 studies.

-28% Heart failure
-27% Heart Stroke
-20% Heart CV events*
-17% Heart Coronary disease
-13% Heart Mortality
-5% Heart Chronic renal failure

-28% Heart failure
-27% Heart Stroke
-20% Heart CV events*
-17% Heart Coronary disease
-13% Heart Mortality
-5% Heart Chronic renal failure

*Defined as fatal and non-fatal myocardial infarction, sudden cardiac death, re-vascularization, fatal and non-fatal stroke, and fatal and non-fatal heart failure

  1. Ettehad et al. Lancet 2016; 387: 957–67

When medication isn’t enough.

Nonadherence increases with increasing drug prescriptions¹

Patients with resistant hypertension struggle to reduce blood pressure due to poor adherence to medication, side effects, and lack of response to medications.

Take renal denervation as a third pillar to treat hypertension.

Ultrasound renal denervation (RDN) can be used as part of a multi-modal approach to treat patients resistant to hypertension.

Discover the Paradise™ Ultrasound Renal Denervation (RDN) system — the first-ever minimally invasive procedure to treat hypertension with ultrasound.